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Sleep issues and anxiety often go hand-in-hand. Just as poor sleep patterns contribute to anxiety, the persistent worries and fears of anxiety can lead to sleep disturbances. This creates a cycle that can be both mentally and physically exhausting.
Luckily, there are ways to find relief, like following a healthy eating plan, exercising regularly, and possibly taking certain supplements. Magnesium, in particular, has garnered a lot of buzz lately thanks to its reputation in some circles as “nature’s chill pill.”
While there isn’t enough scientific research available to say exactly how effective magnesium is at addressing sleep and anxiety concerns, there are some indications that it may help with both.
Below, we break down the different types of magnesium supplements for anxiety and sleep issues, how magnesium might improve symptoms of anxiety and enhance sleep quality, and other ways to treat mental health conditions (like anxiety) and sleep disorders.
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Magnesium is an essential mineral that helps regulate a variety of bodily functions, including managing muscle and nerve activity, protein production, and blood sugar and blood pressure levels.
Because magnesium plays a role in regulating the central nervous system, it may indirectly impact mood and sleep as well.
Many foods contain magnesium, so you can get it from your diet, but dietary supplements can help boost magnesium levels in your body if your diet alone isn’t enough.
On average, men need 300 milligrams of magnesium daily, while women need 270 milligrams a day.
Even though it’s an essential mineral, about 50 percent of Americans get less than the recommended daily amount. The best way to make sure you’re getting enough magnesium is to eat more of these magnesium-rich foods:
Whole grains, like quinoa, brown rice, and oatmeal
Avocado
Leafy greens, like arugula, kale, and spinach
Nuts, especially almonds and cashews, and seeds (like chia and pumpkin seeds)
Legumes, like beans
Dark chocolate
Fish
Fermented foods, like yogurt
Oh, and getting regular exercise can help your body use magnesium more efficiently (and it’s also linked with improved moods and sleep). But, be aware that strenuous exercise can also deplete magnesium levels, making a balanced diet even more important.
It’s helpful to know what signs point to lower levels so you can make a concerted effort to increase your magnesium intake if need be.
Some signs of low magnesium include:
Loss of appetite
Nausea
Vomiting
Fatigue
Constipation
Changes in personality
More intense premenstrual syndrome (PMS)
Numbness and tingling
Muscle weakness, contractions, and cramps
Abnormal heart rhythms or irregular heartbeat
Keep in mind that having lower magnesium levels doesn’t necessarily mean you have a magnesium deficiency.
Not all magnesium supplements are equal. Some are better absorbed by the body, which may make them more effective. They’re also sometimes combined with other ingredients to create certain effects and boost the benefits.
Let’s explore the many different types of magnesium supplements:
Magnesium Malate. A combination of magnesium and malate, this kind of supplement can help with headaches. One study suggests that the body absorbs it very well, contributing to its efficacy.
Magnesium Taurate. This combines magnesium and the amino acid taurine (also naturally produced in the body), which is linked with relaxation. The same study mentioned above found that it was the second-best absorbed form of magnesium.
Magnesium L-Threonate. Some research shows that this type of magnesium is associated with improved cognitive function and sleep quality, though more studies are needed to understand how effective it really is. It’s also pretty well-absorbed by the body.
Magnesium Glycinate. Manufacturers combine this type of magnesium with glycine, an amino acid. The body absorbs this type of magnesium more easily compared to other formulations. Researchers aren’t exactly sure how glycine works, but one animal study found that it helped improve sleep. We have to be careful with animal studies, though, because the same results are often not found in humans. It’s also less likely to interfere with digestion.
Other types of magnesium that aren’t necessarily linked with reducing anxiety and helping with sleep are:
Magnesium Citrate. The body can absorb this form of magnesium quickly and easily, so it’s considered one of the more effective forms. In supplement form, it’s bound with citric acid, but it can be naturally found in oranges, grapefruit, and bananas. It’s sometimes used to help relieve constipation.
Magnesium Chloride. This type of magnesium has chloride in it and is usually sold as a supplement capsule. It’s relatively well-absorbed.
Magnesium Sulfate. This is most commonly used to help relieve constipation in the short term. It’s often found in the form of a powder. Magnesium sulfate is also commonly known as Epsom salt and is used in bath soaks for muscle relaxation.
Magnesium Oxide. This form of magnesium is inorganic, and the body doesn’t absorb it very well, which also means it’s less effective. But because it’s cheap and easy to manufacture, you may see it in some supplements.
So, which is the best one for sleep and anxiety?
The answer is twofold: One, it will probably depend on the underlying reasons for your anxiety and sleep issues. Two, the research isn’t totally clear.
That said, based on the information we do have, magnesium taurate and magnesium glycinate may be the best options for sleep and anxiety.
So, does magnesium help with sleep and anxiety? Study results have been mixed, but some research on magnesium supplements for anxiety and sleep is promising.
Let’s dive into the details of how magnesium could support lower anxiety and better sleep.
When you’re feeling stressed, your body releases cortisol, which is colloquially known as the “stress hormone.” Raised cortisol levels are linked with increased anxiety and elevated blood pressure.
Some research suggests that higher magnesium levels can help lower cortisol levels when you’re feeling stressed. So even if it doesn’t have a direct calming effect, it may help you feel more even-keeled.
According to one review, low levels of magnesium were linked to a variety of mental health conditions, including depression. But the studies didn’t find a definitive link between anxiety disorders (like general anxiety disorder and panic disorder) and low magnesium levels.
Some symptoms of depression are having less energy, difficulty sleeping, and feeling irritable or anxious. So, even though there isn’t much research supporting the effect of magnesium on anxiety, it may help with associated feelings of depression or sleep issues.
Another research review examined how magnesium affects people prone to anxiety, including those with mild anxiety and PMS-related unease.
Some studies they analyzed suggest that magnesium supplementation can help with mild anxiety and PMS-related anxiety. Magnesium may also help with other PMS symptoms, like cramps.
In one study that examined how the amount of magnesium consumed links to sleep quality, participants who got the highest levels of magnesium seemed to get the best night’s sleep. They were also less likely to get too little sleep (seven hours or less a night) than those with low magnesium intake.
This difference appeared more noticeable in people without depression. For those with depression, magnesium didn’t seem to affect their sleep quality or duration.
However, the difference in sleep quality ratings wasn’t significant enough to say for sure if magnesium intake was the reason for the improved sleep quality.
Some studies suggest that magnesium may help some people fall asleep faster and feel less sleepy throughout the day. That said, other studies indicate that there isn’t enough clear evidence to definitively confirm whether or not magnesium actually improves sleep.
Additional research suggests that taking both melatonin and magnesium supplements together might lead to better sleep quality in women with polycystic ovary syndrome (PCOS). Melatonin is a naturally occurring hormone that helps regulate the sleep-wake cycle, but is also available as a supplement to help with sleep.
Restless leg syndrome is one of the most common sleep disorders. It’s marked by a seemingly random urge to move your legs and feet. It usually crops up at night, and the symptoms can lead to anxiety and make it hard to sleep.
So, where does magnesium come into play?
One small study looked at how magnesium and vitamin B6 supplements helped with the symptoms of RLS. Though researchers aren’t totally sure why, this combination helped reduce the severity of RLS symptoms.
If you’re planning on adding magnesium supplements to your nighttime routine, it’s good to be aware of some of the side effects.
The most common side effects of excessive magnesium intake are digestive-related. Since some forms of magnesium supplements are used as mild laxatives, it’s not surprising that they can cause diarrhea. Other side effects of too much magnesium can include:
Nausea and vomiting
Abdominal cramps
Facial flushing
Urine retention (a blockage that can prevent urine from leaving the body)
In general, it’s best to speak with a healthcare professional before adding any new supplements to your routine.
Some people take magnesium to help with sleep issues or anxiety, but there are other, more science-backed ways to treat both conditions.
While everyone gets anxious occasionally, it may be time to reach out to a healthcare provider if your symptoms are persistent and overwhelming. Depending on your concerns, your provider may recommend trying some form of psychotherapy or medication, or a combination of the two.
Some prescription mental health treatments include:
Selective Serotonin Reuptake Inhibitors (SSRIs) are a commonly prescribed class of antidepressants that act on serotonin to treat depression and anxiety. Examples include escitalopram (Lexapro®), sertraline (Lustral and Zoloft®), and fluoxetine (Prozac®).
Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs) are a type of antidepressant that acts on the neurotransmitters serotonin and norepinephrine. They’re often prescribed to treat chronic pain, depression, and anxiety. Examples include duloxetine (Cymablta®) and venlafaxine (Effexor®).
Anti-anxiety medications like buspirone (BuSpar®) are sometimes prescribed to treat generalized anxiety disorder in the short term. Researchers don’t fully understand how it works as an anxiety treatment, but they believe it helps regulate levels of serotonin and dopamine.
Atypical antidepressants like bupropion (Wellbutrin®) are often used to treat depression. Researchers think bupropion works by affecting norepinephrine and dopamine, chemicals in the brain that impact mood, motivation, and more.
If you think you might be a fit for any of the above medications, reach out to a healthcare professional. They’ll talk to you about your symptoms and develop a treatment plan that works for you.
If you have insomnia or another sleep disorder — or your sleep issues are affecting your ability to function — you may also want to talk to your healthcare provider about prescription sleep aids and other treatment options.
Neither anxiety nor sleep problems are fun to deal with — especially when you suffer from both. But there are ways to manage the symptoms. Some studies suggest that magnesium levels may play a role.
Here’s what to keep in mind about magnesium and its relationship to sleep and anxiety:
Magnesium is an essential mineral. To make sure you get enough of it, you should eat a balanced diet with plenty of legumes, greens, lean protein, and whole grains.
The best forms of magnesium for sleep and anxiety are likely magnesium taurate and magnesium glycinate, but the research is still a little shaky.
Some research suggests that magnesium may help with sleep and anxiety by regulating cortisol levels, helping improve mood, alleviating symptoms of PMS and RLS, and making it easier to fall asleep and stay asleep for longer.
Though some research shows that magnesium might help manage symptoms of stress and sleep disturbances, there are other options available with stronger science backing up their efficacy. Medications like prescription sleep aids or antidepressants might be an option.
If you’d like to learn more about managing mental health with medication, you can seek medical advice online through our psychiatry service. Our providers will evaluate your well-being, explain all your options, and work with you to determine which is the best fit for you.
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Dr. Daniel Z. Lieberman is the senior vice president of mental health at Hims & Hers and of psychiatry and behavioral sciences at George Washington University. Prior to joining Hims & Hers, Dr. Lieberman spent over 25 years as a full time academic, receiving multiple awards for teaching and research. While at George Washington, he served as the chairman of the university’s Institutional Review Board and the vice chair of the Department of Psychiatry and Behavioral Sciences.
Dr. Lieberman’s has focused on , , , and to increase access to scientifically-proven treatments. He served as the principal investigator at George Washington University for dozens of FDA trials of new medications and developed online programs to help people with , , and . In recognition of his contributions to the field of psychiatry, in 2015, Dr. Lieberman was designated a distinguished fellow of the American Psychiatric Association. He is board certified in psychiatry and addiction psychiatry by the American Board of Psychiatry and Neurology.
As an expert in mental health, Dr. Lieberman has provided insight on psychiatric topics for the U.S. Department of Health and Human Services, U.S. Department of Commerce, and Office of Drug & Alcohol Policy.
Dr. Lieberman studied the Great Books at St. John’s College and attended medical school at New York University, where he also completed his psychiatry residency. He is the coauthor of the international bestseller , which has been translated into more than 20 languages and was selected as one of the “Must-Read Brain Books of 2018” by Forbes. He is also the author of . He has been on and to discuss the role of the in human behavior, , and .
1992: M.D., New York University School of Medicine
1985: B.A., St. John’s College, Annapolis, Maryland
2022–Present: Clinical Professor, George Washington University Department of Psychiatry and Behavioral Sciences
2013–2022: Vice Chair for Clinical Affairs, George Washington University Department of Psychiatry and Behavioral Sciences
2010–2022: Professor, George Washington University Department of Psychiatry and Behavioral Sciences
2008–2017: Chairman, George Washington University Institutional Review Board
2022: Distinguished Life Fellow, American Psychiatric Association
2008–2020: Washingtonian Top Doctor award
2005: Caron Foundation Research Award
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Lieberman, D. Z., Swayze, S., & Goodwin, F. K. (2011). An automated Internet application to help patients with bipolar disorder track social rhythm stabilization. Psychiatric services (Washington, D.C.), 62(11), 1267–1269. https://ps.psychiatryonline.org/doi/10.1176/ps.62.11.pss6211_1267?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
Lieberman, D. Z., Massey, S. H., & Goodwin, F. K. (2010). The role of gender in single vs married individuals with bipolar disorder. Comprehensive psychiatry, 51(4), 380–385. https://www.sciencedirect.com/science/article/abs/pii/S0010440X0900128X?via%3Dihub
Lieberman, D. Z., Kolodner, G., Massey, S. H., & Williams, K. P. (2009). Antidepressant-induced mania with concomitant mood stabilizer in patients with comorbid substance abuse and bipolar disorder. Journal of addictive diseases, 28(4), 348–355. https://pubmed.ncbi.nlm.nih.gov/20155604
Lieberman, D. Z., Montgomery, S. A., Tourian, K. A., Brisard, C., Rosas, G., Padmanabhan, K., Germain, J. M., & Pitrosky, B. (2008). A pooled analysis of two placebo-controlled trials of desvenlafaxine in major depressive disorder. International clinical psychopharmacology, 23(4), 188–197. https://journals.lww.com/intclinpsychopharm/abstract/2008/07000/a_pooled_analysis_of_two_placebo_controlled_trials.2.aspx